September 27, 2023

Researchers on the College of Würzburg in Germany have developed a conveyable scanner that’s the first to have the ability to picture people utilizing Magnetic Particle Imaging (MPI). The expertise may present a radiation-free different to strategies reminiscent of X-ray fluoroscopy and digital subtraction angiography for minimally invasive endovascular procedures, and is effectively suited to viewing processes reminiscent of blood movement. Earlier inceptions of MPI expertise had been too giant and costly and had been primarily designed to be used in experimental animals. That is the primary model of the expertise that’s sufficiently small for portability and it has been designed for human sufferers. The process includes administering magnetic nanoparticles to the affected person, after which the scanner measures adjustments of their response to a magnetic subject over time to visualise inside processes within the physique.

Medical imaging has reworked how clinicians can examine the inner working of our our bodies, and is a mainstay of medical diagnostics. Nonetheless, that doesn’t imply that it will possibly’t be improved and up to date. A serious limitation of many imaging modalities is their use of ionizing radiation, which might trigger well being dangers for sufferers and healthcare workers alike. Growing radiation-free imaging methods is a noble aim.

“As with positron emission tomography, which depends on the administration of radioactive substances as markers, this technique has the good benefit of being delicate and quick with out ‘seeing’ interfering background indicators from tissue or bone,” mentioned Volker Behr, a researcher concerned within the examine.

This newest imaging modality isn’t new, having been trialed in experimental animals beforehand, however that is the primary time that researchers have created an MPI imager that’s particularly for human sufferers, and which is small and light-weight sufficient to be comparatively simply transportable. The system includes utilizing magnetic nanoparticles as a tracer inside the physique that may have an effect on magnetic fields, offering a measurable sign that reveals dynamic processes inside the physique, reminiscent of blood movement.

“On this course of, the magnetisation of nanoparticles is particularly manipulated with the assistance of exterior magnetic fields, whereby not solely their presence but in addition their spatial place within the human physique may be detected,” mentioned Patrick Vogel, one other researcher concerned within the examine.   

Examine in journal Scientific Experiences: iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions

By way of: University of Würzburg