Throughout successive waves of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), there was a lower in intensive care unit (ICU) admissions throughout ages, whereas ventilatory and oxygen assist assorted by age, based on a research revealed on-line Aug. 21 in JAMA Pediatrics.
Yanshan Zhu, from the College of Queensland in Australia, and colleagues examined whether or not the dominant circulating SARS-CoV-2 VOCs have been related to variations in COVID-19 severity in hospitalized youngsters (youthful than 18 years) utilizing knowledge obtained from 9 international locations throughout three time frames. Timeframes (T) 1, 2, and three have been outlined to characterize intervals of dominance by the ancestral virus, pre-omicron VOCs, and omicron, respectively.
Knowledge have been included for 31,785 hospitalized youngsters and adolescents. The researchers discovered that for youngsters youthful than 5 years, there was a discount in ICU admission throughout successive SARS-CoV-2 waves (T3 versus T1: danger ratios [RRs], 0.56 and 0.61 for youngsters aged 5 years to “These findings spotlight the significance of contemplating completely different pediatric age teams when assessing illness severity in SARS-CoV-2,” the authors write.
Yanshan Zhu et al, Worldwide Pediatric COVID-19 Severity Over the Course of the Pandemic, JAMA Pediatrics (2023). DOI: 10.1001/jamapediatrics.2023.3117
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Pediatric ICU admissions for SARS-CoV-2 decreased throughout waves (2023, September 2)
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